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Cheyham Lodge, 11 Cheam Road, Ewell Village, Epsom, Surrey KT17 1ST

If you live in Epsom or Ewell, don’t keep taking the pills !

Many people may have heard about potential problems with long term use of anti-imflammatories such as neurofen/ibuprofen . The following research published in Medscape adds further evidence to this ;

AMSTERDAM — For patients with osteoarthritis, nonsteroidal anti-inflammatory drugs (NSAIDs) increase the risk for cardiovascular disease to more than twice the rate of the general population, new research shows.

“There’s no cure for people with osteoarthritis, and you have to treat the pain. But when you treat it with NSAIDs, you increase cardiovascular risk,” said Aslam Anis, PhD, from the University of British Columbia in Vancouver, Canada.

NSAIDs are commonly used to treat the stiff joints that osteoarthritis patients experience, especially in the morning. Thinning of the cartilage in joints causes bones to rub against each other, leading to the common symptoms of joint swelling and pain.

“It’s one of those situations when the treatment can be just as bad as the problem,” Anis told Medscape Medical News. “We don’t have solutions.”

Osteoarthritis has already been shown to be an independent risk factor for cardiovascular disease, but Anis and his colleagues wanted to “disentangle” the role of NSAIDs in this association.

The team identified 7743 people with osteoarthritis and an age- and sex-matched cohort of 23,229 people without osteoarthritis from 720,055 administrative health records in British Columbia.

With multivariable Cox proportional hazards models, risk for the primary outcome of cardiovascular disease was estimated to be 23% higher in people with osteoarthritis than in those without after adjustment for age, sex, socioeconomic status, body mass index, hypertension, diabetes, hyperlipidemia, chronic obstructive pulmonary disease, and Romano comorbidity score.

For secondary outcomes, risk for congestive heart failure was 42% higher in people with osteoarthritis, for ischemic heart disease risk was 17% higher, and for stroke risk was 14% higher.

When prescription dispensing records for current NSAID use were linked to the healthcare database, approximately 67.5% of the total effect of osteoarthritis on cardiovascular disease risk was related to NSAID use.

Specifically, the risk for congestive heart failure increased by 44.8% with NSAID use, the risk for ischemic heart disease increased by 94.5%, and the risk for stroke increased by 93.3%.

These results are likely conservative, because the records only captured prescription NSAIDs; the effect of over-the-counter NSAIDs, such as ibuprofen and naproxen, were not accounted for.


Richard Katesmark comments “ It has been known for sometime that taking certain ( in fact most ) anti-imflammatory medications over long periods can have disadvantages & health implications. If you are regularly using these medications, which includes many over-the-counter painkillers, it would be worth having a conversation with your heath specialist/G.P regarding relative risks & benefits.

If people are taking the medications to help reduce joint & muscle pain it is often worth seeing a musculoskeletal specialist. Here at Epsom & Ewell Osteopathic Clinic (https://www.epsomewellosteo.co.uk) many patients find that after assessment & treatment they can stop or at least reduce the number of painkillers they are taking .”